Nov 8, 2024 · Trazodone is an antidepressant often prescribed off-label for sleep. It may be an effective sleep aid with fewer side effects than other options, but it may still pose risks. Learn more.

Dec 11, 2025 · Its action is long enough to cover a typical sleep cycle of 6–8 hours, which includes falling asleep and staying asleep through your light and deep sleep stages. Trazodone’s dosage for …

Dec 20, 2025 · However, the American Academy of Sleep Medicine does not recommend trazodone to treat insomnia based on its overall effectiveness. Research suggests it only reduces the time it takes …

Apr 11, 2025 · Most clinical guidelines suggest using sleep medications like trazodone for no more than 2 to 4 weeks without re-evaluation. Long-term use of trazodone may be appropriate in specific …

Dec 9, 2025 · How long does it take for trazodone to work for sleep? Trazodone can start working within 30 minutes, but it may take up to 2 hours for some people to experience its effects.

Sep 22, 2024 · It is safe to take trazodone for short-term treatment of sleep disturbances. It is regularly prescribed for this purpose with good effect and several trials and reviews have reported positive …

Mar 23, 2025 · Onset Time: Many users experience drowsiness within 30 to 60 minutes after taking the medication. Peak Effect: The strongest sedative effects occur within 1 to 2 hours. Duration: The …

Apr 29, 2025 · FDA Approval: Trazodone is FDA-approved for depression in doses up to 400–600 mg/day. Off-label Sleep Use: Most sleep-related prescribing is below 150 mg, well under the …

Nov 11, 2024 · Beyond mood enhancement, trazodone has sedative effects, which is what makes it a go-to for those struggling with insomnia or sleep disturbances. In essence, it calms the brain and …

Aug 24, 2022 · If you are taking trazodone for insomnia (trouble sleeping), it will begin working (i.e. make you drowsy) about 30 to 60 minutes after taking a dose. If you are taking trazodone for the treatment …