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  1. Major histocompatibility complex, class I-related - Wikipedia

    Major histocompatibility complex class I-related gene protein (MR1) is a non-classical MHC class I protein, that binds vitamin metabolites (intermediates of riboflavin synthesis) produced in certain …

  2. MR-1 CNC Gantry Mill | Langmuir Systems

    Introducing MR-1: the first affordable CNC Mill engineered to cut aluminum and steel. Only $4495 for a limited time. The MR-1 Gantry Mill is a 3-Axis vertical CNC milling machine that was designed …

  3. Molecular Insights Into MR1‐Mediated T Cell Immunity: Lessons …

    The major histocompatibility complex class‐I related protein, MR1, is an evolutionarily conserved antigen presenting molecule that binds and displays organic metabolites to T cells, including mucosal …

  4. MR1 Gene - GeneCards | HMR1 Protein | HMR1 Antibody

    Nov 14, 2025 · MR1 (Major Histocompatibility Complex, Class I-Related) is a Protein Coding gene. Diseases associated with MR1 include Immune Deficiency Disease and Paroxysmal Nonkinesigenic …

  5. MR1, an immunological periscope of cellular metabolism

    Oct 27, 2021 · The paucity of surface-expressed MR1 could indicate that, under homeostatic conditions, self-antigens poorly bind MR1, thus preventing their presentation to T cells.

  6. MR1-Restricted T Cells Are Unprecedented Cancer Fighters

    Apr 28, 2020 · This review will discuss current knowledge regarding the roles of MR1-restricted T cells in cancer and their possible introduction in cell therapy. MR1 is highly conserved among most …

  7. MR1 antigen presentation to MAIT cells and other MR1 ... - Nature

    Sep 29, 2023 · MHC class I-related protein 1 (MR1) presents a range of small molecule antigens to MR1-restricted T (MR1T) lymphocytes. The best studied MR1 ligands are derived from microbial …

  8. Molecular Insights Into MR1-Mediated T Cell Immunity: Lessons …

    May 7, 2025 · The major histocompatibility complex class-I related protein, MR1, is an evolutionarily conserved antigen presenting molecule that binds and displays organic metabolites to T cells, …

  9. MR1-Restricted Immunity in Hematologic Malignancy

    Nov 5, 2024 · Defining conserved MR1 ligands in these blood cancers and the MAIT cell subsets that they induce will inform transformative approaches to MR1-directed cancer immunotherapy.

  10. MR1 antigen presentation to MAIT cells and other MR1-restricted T …

    MHC class I-related protein 1 (MR1) presents a range of small molecule antigens to MR1-restricted T (MR1T) lymphocytes. The best studied MR1 ligands are derived from microbial metabolism and are …