This rare genetic disorder can affect your nerves and cause tumors on the brain and spinal cord that may impact hearing, vision, and balance. Proper treatment and regular monitoring can help manage ...
This slow-growing type of tumor develops on the protective sheath around nerves, usually in the peripheral nervous system. They’re generally not life-threatening, but they require ongoing monitoring ...
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Neurofibromatosis type 2 (NF2-related schwannomatosis) is a genetic condition that causes tumors to grow around nerves, often in the brain and spine. These tumors are usually non-cancerous (benign).
Vivace Therapeutics Inc. reported preclinical efficacy data of VT-3989, a TEAD inhibitor, in in vitro and in vivo models of aggressive meningioma. VT-3989 is in early clinical development for the ...
Researchers at the University of Plymouth are leading an innovative initiative to advance the study of meningiomas in NF2-related schwannomatosis (NF2-SWN). Meningiomas, often linked to the loss of ...
NF2-related schwannomatosis is a relentlessly progressive tumor predisposition syndrome with no FDA-approved treatments. Results from the Phase II INTUITT-NF2 trial (NCT04374305) show brigatinib ...
1. In this randomized controlled trial, brigatinib reduced the size of progressively growing tumors in patients with neurofibromatosis type 2-related schwannomatosis (NF2-SWN). 2. In participants ...
For patients with NF2-related schwannomatosis and progressive tumors, the ALK inhibitor brigatinib (Alunbrig) was associated with radiographic response for multiple tumor types, as well as ...
Drugs used to treat HIV are to be trialled in people with incurable multiple brain tumours. Scientists think ritonavir and lopinavir could shrink tumours in patients with neurofibromatosis 2 (NF2), a ...
Like any specialized field, cancer biology has its fair share of technical vocabulary and jargon; two examples which you may be familiar with are the terms tumor suppressor (a gene whose loss or ...