Transfer RNAs (tRNAs) deliver specific amino acids to ribosomes during translation of messenger RNA into proteins. The abundance of tRNAs can therefore have a profound impact on cell physiology, but ...

The enzymes studied are tRNA nucleotidyltransferases: enzymes that attach three nucleotide building blocks in the sequence C-C-A to small RNAs in the cell (so-called transfer RNAs) so that they can ...

In-depth mass spectrometric analysis reveals how cells survive stress by coordinating various enzymes that modify RNAs involved in protein synthesis. Despite the remarkable functional diversity that ...

A team of researchers led by University of California, Riverside biomedical scientists has identified a small, previously ...

We welcome Drs Nathan Howell and Boaz Tirosh as new faculty members in the Department of Biochemistry! Dr. Howell is an Assistant Professor with research interests in tRNA modification. He is an ...

In a new pharmaphorum podcast, web editor Nicole Raleigh speaks with Dr Alan Roth, CEO of Oxford Drug Design, about the use ...

Two new options for making designer proteins made news in 2001—both from labs at Scripps Research Institute. Since 2001, Schimmel and Schultz have taken different directions with unnatural amino acids ...

Nathalie Reid decided to pursue a career in biochemistry because the field combines her interests in biology, chemistry and mathematics. Now, the first-year PhD candidate in the Department of ...

When studying for a doctoral degree (PhD), candidates submit a thesis that provides a critical review of the current state of knowledge of the thesis subject as well as the student’s own contributions ...

A cell contains several hundred thousand tRNA molecules, each of which consists of only 70 to 90 nucleotides folded into a cloverleaf-like pattern. At one end, tRNAs carry one of the twenty amino ...