The phase 2 BESTOW trial evaluated the safety and efficacy of tegoprubart vs tacrolimus in the prevention of rejection in patients undergoing kidney transplantation.

Children with frequently relapsing or steroid-dependent nephrotic syndrome had a significantly longer relapse-free survival period with tacrolimus than with mycophenolate mofetil. Relapse-free ...

Please provide your email address to receive an email when new articles are posted on . The tacrolimus group had a 1.86-fold higher rate of relapse-free survival vs. those assigned mycophenolate ...

The anti-CD40 antibody tegoprubart offers a tacrolimus-free immunosuppression option for preventing islet transplant ...

Please provide your email address to receive an email when new articles are posted on . Tacrolimus alone had a dose-response relationship with achieving complete renal response in SLE. Combination ...

Typical maintenance immunosuppression is shown in Table 3. It is beyond the scope of this review to go into detail and the readers are referred to UpToDate (www.uptodate.com) for a current discussion ...

Mycophenolic acid (MPA) is a cornerstone immunosuppressive agent in renal transplantation, routinely administered as mycophenolate mofetil or its enteric‐coated counterpart. As a potent, selective and ...

Patients undergoing matched-donor stem cell transplants lived four times longer without episodes of graft-versus-host disease (GVHD) with post-transplant cyclophosphamide-cyclosporin prophylaxis, a ...

This article originally appeared on ProPublica. ProPublica is a Pulitzer Prize-winning investigative newsroom. Sign up for The Big Story newsletter to receive stories like this one in your inbox. Joe ...

ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. Joe DeMayo always knew his healthy years could end abruptly, ...